There are more than 200 zoonotic diseases in humans which pose a public health problem in industrialised countries. The diseases that are transmitted by haematophagous arthropods are most common, causing neurological manifestations or mortality, unless they are detected at an early stage.
At present, differential diagnosis faces two major challenges: there are no commercial direct detection methods and the clinical manifestations are non-specific and often very common.
Vitro has developed the Tick-Borne Bacteria Flow Chip to overcome these challenges. A rapid and sensitive kit that allows the simple simultaneous detection of arthropod-borne bacterial pathogens.
Detection of arthropod-borne bacterial pathogens using multiplex PCR and reverse line blot hybridisation.
Kit details
The Tick-Borne Bacteria Flow Chip is an advanced in vitro diagnostic kit designed to accurately identify arthropod-borne bacterial pathogens. This revolutionary system enables the simultaneous qualitative detection of the most common bacterial species from the Anaplasma, Ehrlichia, Borrelia, Bartonella, Coxiella, Rickettsia and Francisella genera. This method is based on the simultaneous amplification of specific fragments of each genus using multiplex PCR, followed by membrane hybridisation with specific DNA probes using DNA Flow technology, either automatically or manually, thus providing a versatile and effective tool for the accurate diagnosis of these infections. We have managed to increase the sensitivity of this technique and significantly reduce diagnosis times. This approach is crucial in view of the current challenges posed by the differential diagnosis of arthropod-borne pathogens, given the non-specific nature of the clinical manifestations.
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Over 30 years of experience in developing and manufacturing reagents for immunohistochemistry, molecular diagnostic products, instruments and software.
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