Chromogenic in situ hybridisation (CISH) is especially useful in clinical settings for studying biomarkers and genetic alterations associated with diseases such as cancer. As with other ISH techniques, it uses chromogenic detection methods to visualise hybridisation signals.
As part of our diagnostic solutions, Vitro offers a full range of user-friendly «ready-to-use reagents» with optimised protocols, which are highly reliable and compatible with manual and automated processes.
Its advantages include its ability to preserve tissue morphology, allowing molecular information to be correlated with cellular and tissue architecture. This technique is also often used in pathology to analyse gene amplification and expression, as well as chromosome abnormalities in tissue samples.
This technique allows specific nucleic acid sequences to be located and visualised within cells or tissues. It provides a visual representation of molecular events within the tissue structure, which helps us to understand disease mechanisms and potential diagnostic applications.
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